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FAQ
Why don't I see an interaction plot for my mixture experiment?
Original question from a Pharmaceutical Chemist:
“When I am analyzing a factorial design, Stat-Ease software produces a very useful interaction plot. However, this option does not appear to be available for a mixture design. Why is that?”
Answer:
For mixtures, interaction plots cannot be applied because of the total being fixed, thus as one component goes up the other must go down. Instead, our software provides a two-component model-graph such as the one shown below for a mixture case on release of ibuprofen.
The two-component terms in a mixture model, in this case AC, provide an assessment of nonlinearity that cannot be provided by a factorial model. This is just one for the many advantages to applying Stat-Ease software tools for mixtures to development of pharmaceutical or any other formulation—food, chemicals, etc.
(Learn more about non-linear blending by enrolling in the next Mixture Design for Optimal Formulations workshop, or for food scientists, see below for a special industry-focused course.)
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Feel free to get back to me via [email protected] with further questions or comments: I would really appreciate hearing from you!
All the best,
Mark J. Anderson, PE, CQE, MBA
Engineering Consultant, Stat-Ease, Inc.
www.linkedin.com/in/markstat/
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Acquiring knowledge, I've learned is the key,
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